Features:

• High resolution gas chromatographic separation can be achieved for complex samples, when operated in 2-D mode.
• Independent temperature programming for each of the columns possible
• MS can collect > 20 full range spectra across a 50ms GC peak
• High dynamic range can be achieved

Working Principle:

The GC-GC-TOF-MS facility was installed in Centre for Research in Nanotechnology and Science (CRNTS) in January 2016 as a Central Facility as per RIFC norms. The facility is available for meeting the research needs of all IIT Bombay internal users.

It can perform all analysis that a typical GC-TOF-MS can perform. Its particular benefit is for analysis of organic compounds from complex mixtures and environmental samples where high end separation is involved. It involves two columns (that can achieve separation based on different attributes). A thermal modulator ensures cryo focusing of effluent from the first column before its release to the second column. The two-dimensional output helps in resolving the peak of target analytes even when matrix interferences are present. The enhanced spectral collection rate of the TOF-MS detector together with the software capabilities can help in de-convolution of co-eluting compounds.