External users: registration to be carried out only through I-STEM portal
Additional information about sample and analysis details should be filled in the pdf form provided in the I-STEM portal under “DOWNLOAD CSRF”
Internal users (IITB): registration to be carried out only through DRONA portal
Additional information about sample and analysis details should be filled in the pdf form provided here.
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Category
- Spectroscopy and Spectrometry » Mass Spectrometry
Booking Details
Facility Management Team and Location
Facility Features, Working Principle and Specifications
IC-ICP-MS stands for Ion Chromatography coupled with Inductively Coupled Plasma Mass Spectrometry. It's a powerful analytical technique used for speciation analysis—that is, identifying and quantifying different chemical forms of elements, especially metals and metalloids.
Here’s how it works:
- Ion Chromatography (IC) separates different ionic species in a sample based on their charge and size.
- ICP-MS then detects and quantifies these species with extremely high sensitivity, often down to parts per trillion. Aerosol samples are transported into the core of the inductively coupled argon plasma which generates temperatures of 6000-10000 degrees C, where they are completely desolvated and ionized. The resultant ions are separated and collected by mass to charge ratios. The system can detect element from Lithium to Uranium except the noble gases and the elements which do not get converted to positive ions (F).
[Sample] ──► [Ion Chromatograph] ──► [Interface] ──► [ICP Torch] ──► [Mass Spectrometer] ──► [Data Output]
(Separation) (Transfer) (Ionization) (m/z detection)
This combo is especially useful in environmental, food, and pharmaceutical testing. For example, it can distinguish between toxic inorganic arsenic and less harmful organic arsenic in water or food samples.
ICS 6000 Ion Chromatography System
- Quaternary Gradient Pump
- Pressure range 0-41 Mpa (0-6000 psi)
- Temp Range 18 -40 °C
- CD Conductive Detector with integrated flow cell
- Resolution 0.00238 nS/cm
- Digital Signal Range: 0-18,000 µS/cm
- Column for anion, cation
- Columns for Cr As, Hg etc. speciation analysis
- Dionex AS-DV Autosampler
iCAP RQ ICP-MS
- Digital, Solid-state RF- generator with Dynamic frequency
- Computer controlled plasma positioning in all three dimensions, x, y and z
- Plasma Tv- for simplified plasma optimization
- Proprietary QCell with Flatapole technology
- Collision/reaction cell technology (CRC)with TWO CCT gas MFCs
- Mass Range 2-290amu
- Qtegra Control software platform
- ASX560 Autosampler
Speciation
- Chromium (Cr (III) vs Chromium (VI)
- Methylmercury vs Other mercury forms
- Arsenic
Sample Preparation, User Instructions and Precautionary Measures
1. Sample should be submitted in solution form specifying the elements to be estimated and their approximate concentrations expected, but the Total dissolved Solid (TDS) in the solution should not exceed preferably 200 ppm. Dilute accordingly
2. Generally 10 ml of solution is sufficient for estimation of about 10 to 15 elements
3. For special samples like rocks / ore samples, appropriate standards along with the samples should be submitted by user.
4. Explosive, poisonous samples and samples giving rise to toxic gases/fumes cannot be undertaken for ICP-MS analysis.
5. There is no upper limit for the number of samples acceptable for ICP-MS laboratory.
6. The nebulizer of the instrument is made out of PFA material, but spray chambers are of Glass, quartz and PFA, hence user should specify if their samples have HF content.
7. The concentration of analyte in samples should be less than 100 ppb for ICPMS.
8. Kindly provide the standards for e.g. rocks so that Matrix interferences can be avoided.
Charges for Analytical Services in Different Categories
Charges (without GST)
ICP-MS
| IIT Bombay Users | University | National Lab/R&D's | Startup /MSME | Industry |
|
Standarization & Estimation | 300 | 600 | 1500 | 2250 | 3000 | Per sample /element |
Subsequent sample per element | 100 | 200 | 500 | 750 | 1000 | Per sample /element |
Sample Preparation | 600 | 1200 | 3000 | 4500 | 6000 | Per sample |
* For Mercury sample concentration should be < 50 ppb
Ion Chromatography (IC) Anion
| IIT Bombay Users | University | National Lab/R&D's | Startup /MSME | Industry |
Standarization & Estimation (F-, Cl-, NO2-,Br-, ,NO3‑ , PO43-,SO42-) | 500 | 1000 | 2500 | 3750 | 5000 |
Subsequent sample per element | 300 | 600 | 1500 | 2000 | 2500 |
Ion Chromatography (IC) Cation
| IIT Bombay Users | University | National Lab/R&D's | Startup /MSME | Industry |
Standarization & Estimation (Li+, Na+, K+, NH4+ , Mg2+ Ca2+) | 500 | 1000 | 2500 | 3750 | 5000 |
Subsequent sample per element | 300 | 600 | 1500 | 2000 | 2500 |